Milk Thistle (Silymarin) Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated.The optical properties of the prepared azidotriazoles were studied to reveal a luminescence maximum in the 360−420 nm region.To improve the luminescence quantum yields a family of 4-azido-1,2,3-triazoles bearing ortho-propargyloxy substituents in the 5 position was prepared.Subsequent intramolecular thermal cyclization Ringette Ring permits to construct additional triazole fragment and obtain unique benzoxazocine derivatives condensed with two triazole rings.
This new family of condensed heterocycles has a flattened heterocyclic system structure to provide more conjugation of the 5-aryl fragment with the triazole core.As a result, a new type of UV/“blue light-emitting” materials with better photophysical properties was obtained.